The anti-cancer drug Sunitinib promotes autophagy and protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration

Despite the success of antiretroviral therapies to control systemic HIV-1 infection, the prevalence of HIV-associated neurocognitive disorders (HAND) has not decreased among aging patients with HIV. Autophagy pathway alterations, triggered by HIV-1 proteins including gp120, Tat, and Nef, might contr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Fields, Jerel A., Metcalf, Jeff, Overk, Cassia, Adame, Anthony, Spencer, Brian, Wrasidlo, Wolfgang, Florio, Jazmin, Rockenstein, Edward, He, Johnny J., Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729903/
https://ncbi.nlm.nih.gov/pubmed/28105557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-016-0502-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados