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κ-Opioid Receptor Activation in Dopamine Neurons Disrupts Behavioral Inhibition

The dynorphin/κ-opioid receptor (KOR) system has been previously implicated in the regulation of cognition, but the neural circuitry and molecular mechanisms underlying KOR-mediated cognitive disruption are unknown. Here, we used an operational test of cognition involving timing and behavioral inhib...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Abraham, Antony D, Fontaine, Harrison M, Song, Allisa J, Andrews, Mackenzie M, Baird, Madison A, Kieffer, Brigitte L, Land, Benjamin B, Chavkin, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729556/
https://ncbi.nlm.nih.gov/pubmed/28649993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.133
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