Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons

The endogenous dynorphin-κ opioid receptor (KOR) system encodes the dysphoric component of the stress response and controls the risk of depression-like and addiction behaviors; however, the molecular and neural circuit mechanisms are not understood. In this study, we report that KOR activation of p3...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Ehrich, Jonathan M., Messinger, Daniel I., Knakal, Cerise R., Kuhar, Jamie R., Schattauer, Selena S., Bruchas, Michael R., Zweifel, Larry S., Kieffer, Brigitte L., Phillips, Paul E.M., Chavkin, Charles
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4571610/
https://ncbi.nlm.nih.gov/pubmed/26377476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2444-15.2015
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