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Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

Although stress has profound effects on motivated behavior, the underlying mechanisms responsible are incompletely understood. In this study we elucidate a functional pathway in mouse brain that encodes the aversive effects of stress and mediates stress-induced reinstatement of cocaine place prefere...

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Detalhes bibliográficos
Main Authors: Land, Benjamin B., Bruchas, Michael R., Schattauer, Selena, Giardino, William J., Aita, Megumi, Messinger, Daniel, Hnasko, Thomas S., Palmiter, Richard D., Chavkin, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776420/
https://ncbi.nlm.nih.gov/pubmed/19864633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910705106
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