Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation

[Image: see text] Protein aggregation into amyloid fibrils is a ubiquitous phenomenon across the spectrum of neurodegenerative disorders and type 2 diabetes. A common strategy against amyloidogenesis is to minimize the populations of toxic oligomers and protofibrils by inhibiting protein aggregation...

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Publicat a:Biomacromolecules
Autors principals: Pilkington, Emily H., Lai, May, Ge, Xinwei, Stanley, William J., Wang, Bo, Wang, Miaoyi, Kakinen, Aleksandr, Sani, Marc-Antonie, Whittaker, Michael R., Gurzov, Esteban N., Ding, Feng, Quinn, John F., Davis, Thomas P., Ke, Pu Chun
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729549/
https://ncbi.nlm.nih.gov/pubmed/29035554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.7b01301
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