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The BCL-2 arbiters of apoptosis and their growing role as cancer targets

Impaired apoptosis plays a central role in cancer development and limits the efficacy of conventional cytotoxic therapies. Deepening understanding of how opposing factions of the BCL-2 protein family switch on apoptosis and of their structures has driven development of a new class of cancer drugs th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Differ
Päätekijät: Adams, Jerry M, Cory, Suzanne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729526/
https://ncbi.nlm.nih.gov/pubmed/29099483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.161
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