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The Bcl-2 apoptotic switch in cancer development and therapy

Impaired apoptosis is both critical in cancer development and a major barrier to effective treatment. In response to diverse intracellular damage signals, including those evoked by cancer therapy, the cell’s decision to undergo apoptosis is determined by interactions between three factions of the Bc...

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Detalhes bibliográficos
Main Authors: Adams, JM, Cory, S
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930981/
https://ncbi.nlm.nih.gov/pubmed/17322918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210220
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