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The Bcl-2-regulated apoptosis switch: mechanism and therapeutic potential
Apoptosis is essential for tissue homeostasis, particularly in the hematopoietic compartment, where its impairment can elicit neoplastic or autoimmune diseases. Whether stressed cells live or die is largely determined by interplay between opposing members of the Bcl-2 protein family. Bcl-2 and its c...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754308/ https://ncbi.nlm.nih.gov/pubmed/17629468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2007.05.004 |
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