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Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis

BACKGROUND: Meta-analysis shows that women with diabetes have a 20% increased risk of breast cancer and also an increased risk for distant metastasis and mortality. The molecular mechanisms for distant metastasis and mortality in breast cancer patients with diabetes are not very well understood. MET...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Nandy, Sushmita Bose, Orozco, Alexis, Lopez-Valdez, Rebecca, Roberts, Rene, Subramani, Ramadevi, Arumugam, Arunkumar, Dwivedi, Alok Kumar, Stewart, Viktoria, Prabhakar, Gautham, Jones, Stephanie, Lakshmanaswamy, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729435/
https://ncbi.nlm.nih.gov/pubmed/29024936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.335
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