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MicroRNA-125a influences breast cancer stem cells by targeting leukemia inhibitory factor receptor which regulates the hippo signaling pathway

Cancer stem cells (CSC) are the main driving force behind cancer initiation and progression. The molecular mechanisms that regulate CSC properties are poorly understood. MicroRNAs (miRNAs) play a significant role in normal and cancer tissues. Here, we show that miRNA-125a indirectly regulates TAZ, a...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Nandy, Sushmita Bose, Arumugam, Arunkumar, Subramani, Ramadevi, Pedroza, Diego, Hernandez, Keziah, Saltzstein, Edward, Lakshmanaswamy, Rajkumar
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627314/
https://ncbi.nlm.nih.gov/pubmed/25962054
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