Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis

BACKGROUND: Meta-analysis shows that women with diabetes have a 20% increased risk of breast cancer and also an increased risk for distant metastasis and mortality. The molecular mechanisms for distant metastasis and mortality in breast cancer patients with diabetes are not very well understood. MET...

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Vydáno v:Br J Cancer
Hlavní autoři: Nandy, Sushmita Bose, Orozco, Alexis, Lopez-Valdez, Rebecca, Roberts, Rene, Subramani, Ramadevi, Arumugam, Arunkumar, Dwivedi, Alok Kumar, Stewart, Viktoria, Prabhakar, Gautham, Jones, Stephanie, Lakshmanaswamy, Rajkumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729435/
https://ncbi.nlm.nih.gov/pubmed/29024936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.335
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