Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis

BACKGROUND: Meta-analysis shows that women with diabetes have a 20% increased risk of breast cancer and also an increased risk for distant metastasis and mortality. The molecular mechanisms for distant metastasis and mortality in breast cancer patients with diabetes are not very well understood. MET...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Nandy, Sushmita Bose, Orozco, Alexis, Lopez-Valdez, Rebecca, Roberts, Rene, Subramani, Ramadevi, Arumugam, Arunkumar, Dwivedi, Alok Kumar, Stewart, Viktoria, Prabhakar, Gautham, Jones, Stephanie, Lakshmanaswamy, Rajkumar
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Molecular Diagnostics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729435/
https://ncbi.nlm.nih.gov/pubmed/29024936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.335
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