Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis

BACKGROUND: Meta-analysis shows that women with diabetes have a 20% increased risk of breast cancer and also an increased risk for distant metastasis and mortality. The molecular mechanisms for distant metastasis and mortality in breast cancer patients with diabetes are not very well understood. MET...

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Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Nandy, Sushmita Bose, Orozco, Alexis, Lopez-Valdez, Rebecca, Roberts, Rene, Subramani, Ramadevi, Arumugam, Arunkumar, Dwivedi, Alok Kumar, Stewart, Viktoria, Prabhakar, Gautham, Jones, Stephanie, Lakshmanaswamy, Rajkumar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Molecular Diagnostics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729435/
https://ncbi.nlm.nih.gov/pubmed/29024936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.335
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