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PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors
Selective inhibitors for each serine/threonine phosphatase (PPP) are essential to investigate the biological actions of PPPs and to guide drug development. Biologically diverse organisms (e.g., cyanobacteria, dinoflagellates, beetles) produce structurally distinct toxins that are catalytic inhibitor...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5729109/ https://ncbi.nlm.nih.gov/pubmed/29156132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09368 |
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