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Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme

Glycogen is the primary storage form of glucose. Glycogen synthesis and breakdown are tightly controlled by glycogen synthase (GYS) and phosphorylase, respectively. The enzyme responsible for dephosphorylating GYS and phosphorylase, which results in their activation (GYS) or inactivation (phosphoryl...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Kumar, Ganesan Senthil, Choy, Meng S., Koveal, Dorothy M., Lorinsky, Michael K., Lyons, Scott P., Kettenbach, Arminja N., Page, Rebecca, Peti, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235537/
https://ncbi.nlm.nih.gov/pubmed/30443599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6044
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