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Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme

Glycogen is the primary storage form of glucose. Glycogen synthesis and breakdown are tightly controlled by glycogen synthase (GYS) and phosphorylase, respectively. The enzyme responsible for dephosphorylating GYS and phosphorylase, which results in their activation (GYS) or inactivation (phosphoryl...

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Publicat a:Sci Adv
Autors principals: Kumar, Ganesan Senthil, Choy, Meng S., Koveal, Dorothy M., Lorinsky, Michael K., Lyons, Scott P., Kettenbach, Arminja N., Page, Rebecca, Peti, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235537/
https://ncbi.nlm.nih.gov/pubmed/30443599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6044
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