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Aurora B opposes PP1 function in mitosis through phosphorylation of the conserved RVxF binding motif in PP1 regulatory proteins
Protein phosphatase 1 (PP1) is a highly conserved protein phosphatase that performs the majority of serine and threonine (Ser-Thr) dephosphorylation reactions in eukaryotes and opposes the actions of a diverse set of Ser-Thr protein kinases. PP1 gains substrate specificity through binding to a large...
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| Veröffentlicht in: | Sci Signal |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6454879/ https://ncbi.nlm.nih.gov/pubmed/29764992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai8669 |
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