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Aurora B opposes PP1 function in mitosis through phosphorylation of the conserved RVxF binding motif in PP1 regulatory proteins

Protein phosphatase 1 (PP1) is a highly conserved protein phosphatase that performs the majority of serine and threonine (Ser-Thr) dephosphorylation reactions in eukaryotes and opposes the actions of a diverse set of Ser-Thr protein kinases. PP1 gains substrate specificity through binding to a large...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Nasa, Isha, Rusin, Scott F., Kettenbach, Arminja N., Moorhead, Greg B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454879/
https://ncbi.nlm.nih.gov/pubmed/29764992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai8669
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