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Global assessment of its network dynamics reveals that polo-like kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity
Polo-like kinase 1 (Plk1) is an essential protein kinase that promotes faithful mitotic progression in eukaryotes. The subcellular localization and substrate interactions of Plk1 are tightly controlled and require its binding to phosphorylated sequences. Here, to identify phosphorylation-dependent i...
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| Publicado no: | Sci Signal |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002859/ https://ncbi.nlm.nih.gov/pubmed/29764989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq1441 |
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