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The output of protein-coding genes shifts to circular RNAs when the pre-mRNA processing machinery is limiting
Many eukaryotic genes generate linear mRNAs and circular RNAs, but it is largely unknown how the ratio of linear to circular RNA is controlled or modulated. Using RNAi screening in Drosophila cells, we identify many core spliceosome and transcription termination factors that control the RNA outputs...
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| 出版年: | Mol Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728686/ https://ncbi.nlm.nih.gov/pubmed/29174924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.034 |
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