Llwytho...

The output of protein-coding genes shifts to circular RNAs when the pre-mRNA processing machinery is limiting

Many eukaryotic genes generate linear mRNAs and circular RNAs, but it is largely unknown how the ratio of linear to circular RNA is controlled or modulated. Using RNAi screening in Drosophila cells, we identify many core spliceosome and transcription termination factors that control the RNA outputs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Liang, Dongming, Tatomer, Deirdre C., Luo, Zheng, Wu, Huang, Yang, Li, Chen, Ling-Ling, Cherry, Sara, Wilusz, Jeremy E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728686/
https://ncbi.nlm.nih.gov/pubmed/29174924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.034
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