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DNA and factor VII–activating protease protect against the cytotoxicity of histones
Circulating histones have been implicated as major mediators of inflammatory disease because of their strong cytotoxic effects. Histones form the protein core of nucleosomes; however, it is unclear whether histones and nucleosomes are equally cytotoxic. Several plasma proteins that neutralize histon...
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| 發表在: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728637/ https://ncbi.nlm.nih.gov/pubmed/29296900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017010959 |
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