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Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

In inflammation, extensive cell death may occur, which results in the release of chromatin components into the extracellular environment. Individually, the purified chromatin components double stranded (ds)DNA and histones have been demonstrated, both in vitro and in vivo, to display various immunos...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Marsman, Gerben, Zeerleder, Sacha, Luken, Brenda M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261016/
https://ncbi.nlm.nih.gov/pubmed/27929534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.410
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