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Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

In inflammation, extensive cell death may occur, which results in the release of chromatin components into the extracellular environment. Individually, the purified chromatin components double stranded (ds)DNA and histones have been demonstrated, both in vitro and in vivo, to display various immunos...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Marsman, Gerben, Zeerleder, Sacha, Luken, Brenda M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5261016/
https://ncbi.nlm.nih.gov/pubmed/27929534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.410
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