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DNA and factor VII–activating protease protect against the cytotoxicity of histones
Circulating histones have been implicated as major mediators of inflammatory disease because of their strong cytotoxic effects. Histones form the protein core of nucleosomes; however, it is unclear whether histones and nucleosomes are equally cytotoxic. Several plasma proteins that neutralize histon...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728637/ https://ncbi.nlm.nih.gov/pubmed/29296900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017010959 |
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