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Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations

While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood. Here we investigated thermally-activated spontaneous nucleosome sliding mechanisms developing and applying a co...

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Foilsithe in:PLoS Comput Biol
Main Authors: Niina, Toru, Brandani, Giovanni B., Tan, Cheng, Takada, Shoji
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728581/
https://ncbi.nlm.nih.gov/pubmed/29194442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005880
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