Loss of mDia1 causes neutropenia via attenuated CD11b endocytosis and increased neutrophil adhesion to the endothelium

Formin protein mDia1 is involved in actin polymerization and plays important roles in the migration and adhesion of hematopoietic cells. The mDia1 encoding gene is located on chromosome 5q, which is commonly deleted in patients with del(5q) myelodysplastic syndromes (MDSs). We previously reported th...

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Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Mei, Yang, Feng, Gong, Rahimi, Nina, Zhao, Baobing, Zhang, Jingxin, Cao, Lan, Yang, Jing, Gao, Juehua, Chen, Yihua, Sumagin, Ronen, Muller, William A., Zhang, Ling, Ji, Peng
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728338/
https://ncbi.nlm.nih.gov/pubmed/29296812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007906
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