FTY720 protects against ischemic white matter damage by modulating microglia toward M2 polarization via STAT3 pathway

BACKGROUND AND PURPOSE: White matter (WM) ischemic injury, a major neuropathological feature of cerebral small vessel diseases, is an important cause of vascular cognitive impairment in later life. The pathogenesis of demyelination following WM ischemic damage are often accompanied by microglial act...

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Detaylı Bibliyografya
Yayımlandı:Stroke
Asıl Yazarlar: Qin, Chuan, Fan, Wen-Hui, Liu, Qian, Shang, Ke, Murugan, Madhuvika, Wu, Long-Jun, Wang, Wei, Tian, Dai-Shi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728178/
https://ncbi.nlm.nih.gov/pubmed/29114096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.018505
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