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FTY720 protects against ischemic white matter damage by modulating microglia toward M2 polarization via STAT3 pathway
BACKGROUND AND PURPOSE: White matter (WM) ischemic injury, a major neuropathological feature of cerebral small vessel diseases, is an important cause of vascular cognitive impairment in later life. The pathogenesis of demyelination following WM ischemic damage are often accompanied by microglial act...
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| Publicado no: | Stroke |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728178/ https://ncbi.nlm.nih.gov/pubmed/29114096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.018505 |
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