Deficiency in the voltage-gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke

Microglia become activated during cerebral ischemia and exert pro-inflammatory or anti-inflammatory role dependent of microglial polarization. NADPH oxidase (NOX)-dependent reactive oxygen species (ROS) production in microglia plays an important role in neuronal damage after ischemic stroke. Recentl...

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Bibliographic Details
Published in:J Neurochem
Main Authors: Tian, Dai-Shi, Li, Chun-Yu, Qin, Chuan, Murugan, Madhuvika, Wu, Long-Jun, Liu, Jun-Li
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037018/
https://ncbi.nlm.nih.gov/pubmed/27470181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13751
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