Microglial TLR4-dependent autophagy induces ischemic white matter damage via STAT1/6 pathway

Rationale: Ischemic white matter damage frequently results in myelin loss, accompanied with microglial activation. We previously found that directing microglia towards an anti-inflammatory phenotype provided a beneficial microenvironment and helped maintain white matter integrity during chronic cere...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Qin, Chuan, Liu, Qian, Hu, Zi-Wei, Zhou, Luo-Qi, Shang, Ke, Bosco, Dale B., Wu, Long-Jun, Tian, Dai-Shi, Wang, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276098/
https://ncbi.nlm.nih.gov/pubmed/30555556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.27882
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