A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors

The fetal liver is the site of a major expansion of the hematopoietic stem cell (HSC) pool and is also a privileged organ to study megakaryocyte progenitor differentiation. We identified in the mouse fetal liver at day 13.5 a discrete stromal cell population harboring a CD45(−)TER119(−)CD31(−)CD51(+...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Brouard, Nathalie, Jost, Camille, Matthias, Nadine, Albrecht, Camille, Egard, Sébastien, Gandhi, Poojabahen, Strassel, Catherine, Inoue, Tomoko, Sugiyama, Daisuke, Simmons, Paul J., Gachet, Christian, Lanza, Francois
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2017
Subjects:
Platelets and Thrombopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728093/
https://ncbi.nlm.nih.gov/pubmed/29296832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003541
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