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Clonal evolution underlying leukemia progression and Richter transformation in patients with ibrutinib-relapsed CLL
Ibrutinib has generated remarkable responses in patients with chronic lymphocytic leukemia (CLL), including those with an unfavorable cytogenetic profile. However, patients develop resistance, with poor outcomes and no established treatment options. Mutations in BTK and PLCG2 have emerged as main me...
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| 出版年: | Blood Adv |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5728051/ https://ncbi.nlm.nih.gov/pubmed/29296715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016003632 |
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