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A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases
Histidine kinases are key regulators in the bacterial two-component systems that mediate the cellular response to environmental changes. The vast majority of the sensor histidine kinases belong to the bifunctional HisKA family, displaying both kinase and phosphatase activities toward their substrate...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727384/ https://ncbi.nlm.nih.gov/pubmed/29235472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02310-9 |
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