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Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases

Histidine is a versatile residue playing key roles in enzyme catalysis thanks to the chemistry of its imidazole group that can serve as nucleophile, general acid or base depending on its protonation state. In bacteria, signal transduction relies on two-component systems (TCS) which comprise a sensor...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Mideros-Mora, Cristina, Miguel-Romero, Laura, Felipe-Ruiz, Alonso, Casino, Patricia, Marina, Alberto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005713/
https://ncbi.nlm.nih.gov/pubmed/32034139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14540-5
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