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Involvement of Histidine Residue His382 in pH Regulation of MCT4 Activity
Monocarboxylate transporter 4 (MCT4) is a pH-dependent bi-directional lactate transporter. Transport of lactate via MCT4 is increased by extracellular acidification. We investigated the critical histidine residue involved in pH regulation of MCT4 function. Transport of lactate via MCT4 was measured...
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| Published in: | PLoS One |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412719/ https://ncbi.nlm.nih.gov/pubmed/25919709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122738 |
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