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Crucial Residue Involved in L-Lactate Recognition by Human Monocarboxylate Transporter 4 (hMCT4)

BACKGROUND: Monocarboxylate transporters (MCTs) transport monocarboxylates such as lactate, pyruvate and ketone bodies. These transporters are very attractive therapeutic targets in cancer. Elucidations of the functions and structures of MCTs is necessary for the development of effective medicine wh...

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Detalhes bibliográficos
Main Authors: Sasaki, Shotaro, Kobayashi, Masaki, Futagi, Yuya, Ogura, Jiro, Yamaguchi, Hiroaki, Takahashi, Natsuko, Iseki, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729688/
https://ncbi.nlm.nih.gov/pubmed/23935841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067690
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