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Megalin Contributes to Kidney Accumulation and Nephrotoxicity of Colistin

Interest has recently been shown again in colistin because of the increased prevalence of infections caused by multidrug-resistant Gram-negative bacteria. Although the potential for nephrotoxicity is a major dose-limiting factor in colistin use, little is known about the mechanisms that underlie col...

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Detalhes bibliográficos
Main Authors: Suzuki, Takahiro, Yamaguchi, Hiroaki, Ogura, Jiro, Kobayashi, Masaki, Yamada, Takehiro, Iseki, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837877/
https://ncbi.nlm.nih.gov/pubmed/24100504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00254-13
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