In vivo imaging xenograft models for the evaluation of anti‐brain tumor efficacy of targeted drugs

Molecular‐targeted drugs are generally effective against tumors containing driver oncogenes, such as EGFR,ALK, and NTRK1. However, patients harboring these oncogenes frequently experience a progression of brain metastases during treatment. Here, we present an in vivo imaging model for brain tumors u...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Kita, Kenji, Arai, Sachiko, Nishiyama, Akihiro, Taniguchi, Hirokazu, Fukuda, Koji, Wang, Rong, Yamada, Tadaaki, Takeuchi, Shinji, Tange, Shoichiro, Tajima, Atsushi, Nakada, Mitsutoshi, Yasumoto, Kazuo, Motoo, Yoshiharu, Murakami, Takashi, Yano, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727243/
https://ncbi.nlm.nih.gov/pubmed/29125233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1255
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