A miR-327–FGF10–FGFR2-mediated autocrine signaling mechanism controls white fat browning

Understanding the molecular mechanisms regulating beige adipocyte formation may lead to the development of new therapies to combat obesity. Here, we report a miRNA-based autocrine regulatory pathway that controls differentiation of preadipocytes into beige adipocytes. We identify miR-327 as one of t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fischer, Carina, Seki, Takahiro, Lim, Sharon, Nakamura, Masaki, Andersson, Patrik, Yang, Yunlong, Honek, Jennifer, Wang, Yangang, Gao, Yanyan, Chen, Fang, Samani, Nilesh J., Zhang, Jun, Miyake, Masato, Oyadomari, Seiichi, Yasue, Akihiro, Li, Xuri, Zhang, Yun, Liu, Yizhi, Cao, Yihai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727036/
https://ncbi.nlm.nih.gov/pubmed/29233981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02158-z
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