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Monobactam formation in sulfazecin by a non-ribosomal peptide synthetase thioesterase
The N-sulfonated monocyclic β-lactam ring characteristic of the monobactams confers resistance to zinc metallo-β-lactamases and affords the most effective class to combat carbapenem-resistant enterobacteria (CRE). Here we report unprecedented non-ribosomal peptide synthetase activities where an asse...
Tallennettuna:
| Julkaisussa: | Nat Chem Biol |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726899/ https://ncbi.nlm.nih.gov/pubmed/29155429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2526 |
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