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Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster
The monobactams, exemplified by the natural product sulfazecin, are the only class of β-lactam antibiotics not inactivated by metallo-β-lactamases, which confer bacteria with extended-spectrum β-lactam resistance. We screened a transposon mutagenesis library from Pseudomonas acidophila ATCC 31363 an...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5286544/ https://ncbi.nlm.nih.gov/pubmed/28017601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.11.010 |
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