Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

Numerous groups have documented that Ascorbic Acid (AA) promotes cardiomyocyte differentiation from both mouse and human ESCs and iPSCs. AA is now considered indispensable for the routine production of hPSC-cardiomyocytes (CMs) using defined media; however, the mechanisms involved with the inductive...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Perino, Maria Grazia, Yamanaka, Satoshi, Riordon, Daniel R., Tarasova, Yelena, Boheler, Kenneth R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726630/
https://ncbi.nlm.nih.gov/pubmed/29232368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188569
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