Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

Numerous groups have documented that Ascorbic Acid (AA) promotes cardiomyocyte differentiation from both mouse and human ESCs and iPSCs. AA is now considered indispensable for the routine production of hPSC-cardiomyocytes (CMs) using defined media; however, the mechanisms involved with the inductive...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Perino, Maria Grazia, Yamanaka, Satoshi, Riordon, Daniel R., Tarasova, Yelena, Boheler, Kenneth R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5726630/
https://ncbi.nlm.nih.gov/pubmed/29232368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188569
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