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Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin

BACKGROUND: Embryonic stem (ES) cells differentiate into cardiac phenotypes representing early pacemaker-, atrial-, ventricular-, and sinus node-like cells, however, ES-derived specification into sinus nodal cells is not yet known. By using the naphthylamine derivative of urea, suramin, we were able...

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Detalhes bibliográficos
Publicado no:Int J Cardiol
Main Authors: Wiese, Cornelia, Nikolova, Teodora, Zahanich, Ihor, Sulzbacher, Sabine, Fuchs, Joerg, Yamanaka, Satoshi, Graf, Eva, Ravens, Ursula, Boheler, Kenneth R., Wobus, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751033/
https://ncbi.nlm.nih.gov/pubmed/19775764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2009.08.021
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