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The PI3K pathway in human disease
Phosphoinositide 3-kinase (PI3K) activity is stimulated by diverse oncogenes and growth factor receptors, and elevated PI3K signaling is considered a hallmark of cancer. Many PI3K pathway-targeted therapies have been tested in oncology trials, resulting in regulatory approval of one isoform-selectiv...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5726441/ https://ncbi.nlm.nih.gov/pubmed/28802037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.07.029 |
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