ロード中...

Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes

BACKGROUND: Due to its neurotoxic properties, oligomeric alpha-synuclein (α-syn) has been suggested as an attractive target for passive immunization against Parkinson’s disease (PD). In mouse models of PD, antibody treatment has been shown to lower the levels of pathogenic α-syn species, including o...

詳細記述

保存先:
書誌詳細
出版年:J Neuroinflammation
主要な著者: Gustafsson, Gabriel, Lindström, Veronica, Rostami, Jinar, Nordström, Eva, Lannfelt, Lars, Bergström, Joakim, Ingelsson, Martin, Erlandsson, Anna
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725978/
https://ncbi.nlm.nih.gov/pubmed/29228971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1018-z
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!