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Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes
Many lines of evidence suggest that the Parkinson's disease (PD)-related protein α-synuclein (α-SYN) can propagate from cell to cell in a prion-like manner. However, the cellular mechanisms behind the spreading remain elusive. Here, we show that human astrocytes derived from embryonic stem cell...
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| Publicat a: | J Neurosci |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719970/ https://ncbi.nlm.nih.gov/pubmed/29089438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0983-17.2017 |
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