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Novel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer

The present study demonstrates the promising anticancer effects of novel C-substituted diindolylmethane (DIM) derivatives DIM-10 and DIM-14 in aggressive TNBC models. In vitro studies demonstrated that these compounds possess strong anticancer effects. Caco-2 permeability studies resulted in poor pe...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Biopharm
Main Authors: Godugu, Chandraiah, Doddapaneni, Ravi, Safe, Stephen H., Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725228/
https://ncbi.nlm.nih.gov/pubmed/27586082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2016.08.006
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