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Piperlongumine for enhancing oral bioavailability and cytotoxicity of docetaxel in triple negative breast cancer
Very low oral bioavailability due to extensive pre-systemic metabolism and P-gp efflux has constrained the oral metronomic chemotherapy of docetaxel (DTX). There is tremendous need of compounds facilitating oral delivery of DTX. The research was aimed to investigate the effect of piperlongumine (PPL...
Guardat en:
| Publicat a: | J Pharm Sci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706797/ https://ncbi.nlm.nih.gov/pubmed/26372815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24637 |
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