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Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity

PURPOSE: In an effort to prepare an oral dosage form for poorly bioavailable anti-cancer agents, we have incorporated spray drying using a customized spray gun generating enteric coated Self-emulsifying drug delivery systems. The objective of this study was to design and evaluate pharmacokinetics an...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Patel, Apurva R., Godugu, Chandraiah, Wilson, Heather, Safe, Stephen, Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725226/
https://ncbi.nlm.nih.gov/pubmed/25576245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1620-7
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