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Engineering PTEN-L for Cell-Mediated Delivery
The tumor suppressor PTEN is frequently inactivated in glioblastoma. PTEN-L is a long form of PTEN produced by translation from an alternate upstream start codon. Unlike PTEN, PTEN-L has a signal sequence and a tract of six arginine residues that allow PTEN-L to be secreted from cells and be taken u...
Enregistré dans:
| Publié dans: | Mol Ther Methods Clin Dev |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Gene & Cell Therapy
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5725211/ https://ncbi.nlm.nih.gov/pubmed/29255742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.11.006 |
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